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- W2350954805 abstract "Objective To observe the immunosuppression function of a novel HLA derived peptide, RDP1258, and to investigate the mechanisms. Methods The peptides derived from HLA, RDP1258, and HLA 2702.75 84 was synthesized chemically. The effects of the peptides on alloreactive cytotoxic activities of rat spleen cells were observed using 3H TdR incorporation method. The heme oxygenase 1 activity was detected by the enzyme chemistry method. Result The synthetic HLA derived peptides could obviously inhibit the proliferation of rat spleen cells and HO 1 activity in a dose dependent manner in vitro. Conclusion HO 1 may participate in the process of inhibitory effect of RDP1258 on the proliferation of rat spleen cells induced by mitogen or isoantigen." @default.
- W2350954805 created "2016-06-24" @default.
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- W2350954805 date "2005-01-01" @default.
- W2350954805 modified "2023-09-25" @default.
- W2350954805 title "The inhibitory effects of a novel HLA-derived peptide on the immune function of rat splenocytes" @default.
- W2350954805 hasPublicationYear "2005" @default.
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