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- W2351010394 abstract "OBJECTIVE: A randomized comparative open trial was conducted to evaluate the efficacy and safety of levofloxacin iv. compared to ciprofloxacin iv. METHODS:The dose of levofloxacin iv was 200-300mg, bid and the duration of treatment was 7-14days; the dose of ciprofloxacin iv. was 200-400mg, bid for 7-14 days. The total number of final clinical evaluated subjects was 218 including 108 subjects in levofloxacin iv treatment group (L group) and 110 subjects for ciprofloxacin iv. treatment group(C group). The bacterial evaluated subjects were 91 for L group and 88 for C group. RESULTS: show clinical efficacy rate and microbiologic eradication rate for L group were 99. 1% and 92.4%, respectively; Clinical efficacy rate and microbiologic eradication rate for C group was separately 96.4% and 93.3%. The incidence of adverse reaction including whole clinical reactions and laboratory abnormalities was 8.3% for L group and 8.9% for C group. CONCLUSION:It was concluded that levofloxacin had an excellent clinical efficacy and good safety profile in treating patients with bacterial infections." @default.
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- W2351010394 date "2001-01-01" @default.
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- W2351010394 title "A Randomized Comparative Clinical Study of Levofloxacin iv. vs Ciprofloxacin iv. in Treatment of Bacterial Infections" @default.
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