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- W2351036611 abstract "Objective To study the application value of detection of urine and serum levels of mesothelin and serum levels of CA125 in the diagnosis of ovarian epithelial cancer.Methods Mesothelin and CA125 serum levels and mesothelin urine levels in patients with ovarian tumor(41 ovarian epithelial cancer,32 benign ovarian tumor)and 30 healthy women as controls were determined by ELISA,in physical laboratory of Zhengzhou University,in April of 2009.Results The serum mesothelin and urinary mesothelin levels before surgery of patients with ovarian epithelial carcinomas were significantly higher than those of patients with ovarian benign tumor and control group(P0.01).The serum mesothelin and mesothelin levels were not significantly different between patients with ovarian benign tumor and control group(P0.05).The sensitivity and accuracy of serum mesothelin were 58.5% and 83.9%,combined with CA125 they went to 85.4% and 85.5%.The sensitivity and accuracy of urinary mesothelin were 68.3% and 93.5%,combined with CA125 they went to 92.7% and 96.8%.Combination of serum mesothelin and urinary mesothelin and CA125,the sensitivity and accuracy were 95.1% and 96.8%.Conclusion The levels of serum mesothelin together with CA125 or urinary mesothelin together with CA125 can promote the diagnosis of ovarian cancer." @default.
- W2351036611 created "2016-06-24" @default.
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- W2351036611 date "2011-01-01" @default.
- W2351036611 modified "2023-09-23" @default.
- W2351036611 title "The clinical diagnostic value of combined determination of mesothelin with serum CA125 in ovarian epithelial cancer" @default.
- W2351036611 hasPublicationYear "2011" @default.
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