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- W2351041735 abstract "Objective: To study the osteogenesis mechanism in mandibular distraction osteogenesis by comparison investigation between gradual distraction and acute lengthening. Methods: 24 adult dogs were randomly divided into gradually distracted group (n=12) and acutely lengthened group(n=12).4 animals were respectively sacrificed in the 6th day of distraction, 2,8 weeks after completion of distraction and corresponding time in two groups. The change of histology were observed by HE micrograph examination. Results: In gradually distracted group, the distraction gaps were nearly completely ossified after 8 weeks of consolidation, the major mode of new bone formation appears to be intramembranous ossification, few endochondral ossification takes place; In acutely lengthened group, active endochondral ossification existed along the osteotomized bone edges in early stage too, but the major mode of new bone formation appeared change to be endochondral ossification after 2 weeks ,fibril connective tissue and endochondral tissue were filled in the medial area 8 weeks. Conclusions: The major mode of new born formation in distraction osteogenesis is intramenbranous ossification, and result in bone union;the formation of new bone in acutely lengthening is not efficient, lead to unhealthy union." @default.
- W2351041735 created "2016-06-24" @default.
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- W2351041735 date "2004-01-01" @default.
- W2351041735 modified "2023-09-26" @default.
- W2351041735 title "The Observation of Histological Change in Mandibular Distraction Osteogenesis and Acute Lengthening" @default.
- W2351041735 hasPublicationYear "2004" @default.
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