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- W2351044444 abstract "Objective To investigate the relationship between Metabolic Syndrome and cognitive impairment in old population.Methods Totally 90 patients hospitalized in Geriatric Department of Huashan Hospital were assigned to 3 groups according to diseases:MetS with DM/IGT,MetS without DM,Normal.All the patients were examined with SPECT and Wais-RC Test.Insulin resistance was estimated by the Insulin Resistance Index of Homeostasis Model Assessment.Results Significant differences were found in perfusions at most lobes in MetS patients with or without DM/IGT and in controls (P0.05).We found perfusion at left basal ganglia,right parietal,right temporal and cingular gyrus were lower in MetS patients with DM/IGT than those without DM.FIQ declined gradually by groups of normal,MetS without DM/IGT and MetS with DM/IGT.HOMA-IR were higher in both MetS groups than in normal,but showed no different between MetS patients with and without DM/IGT.Conclusions MetS may be the risk factor of aging cognitive impairment.Accelerated cerebrovascular atherosclerosis and increased insulin resistance may contribute to cognitive decline in MetS patients." @default.
- W2351044444 created "2016-06-24" @default.
- W2351044444 creator A5012374085 @default.
- W2351044444 date "2008-01-01" @default.
- W2351044444 modified "2023-09-28" @default.
- W2351044444 title "Insulin resistance,cerebral blood flow and cognitive function in elderly patients with metabolic syndrome" @default.
- W2351044444 hasPublicationYear "2008" @default.
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