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- W2351058598 abstract "Objective: To explore the effects of hyperbaric oxygen on prostaglandins in the cerebral tissue of guinea pigs during fast decompression. Methods: 45 guinea pigs were divided into 3 groups randomly: fast decompression group (FDC), hyperbaric oxygen group (HBO), control group. Animals in FDC group and HBO group were treated with fast decompression and formed decompression sickness. The HBO group were exposed to 0.25 MPa for 60 min after decompression, but the control group were not treated with decompression and not exposed to HBO. The contents of prostaglandin E 2(PGE 2), 6-keto-prostaglandin F 1a (6-K-PGF 1a ) and thromboxane B 2(TXB 2) in the cerebral tissue of animals were measured by enzyme immunoassay. Results: The PGE 2 content in the cerebral tissue of the BHO group were decreased to 2% of that in the FDC group; the TXB 2 content in the cerebral tissue of the HBO group were decreased to 35% of that in the FDC group; and the 6-K-PGF 1a value in the cerebral tissue of the HBO group were decreased to 22% of that in the FDC group. There were significant differences in PGE 2, TXB 2, 6-K-PGF 1a in cerebral tissue between the HBO group and the FDC group (P0.01). Conclusion: HBO can markedly reduce the PGs content in animal cerebral tissue after fast decompression." @default.
- W2351058598 created "2016-06-24" @default.
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- W2351058598 date "2003-01-01" @default.
- W2351058598 modified "2023-09-25" @default.
- W2351058598 title "Effects of Hyperbaric Oxygen on Prostaglandins in the Cerebral Tissue of Guinea Pigs during Fast Decompression" @default.
- W2351058598 hasPublicationYear "2003" @default.
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