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- W2351104586 abstract "Objective To investigate the effects of oxymatrine (OMT) on blood pressure in rats. Methods Fourty-eight Wistar rats were randomly divided into 6 groups (n=8):normal saline group,OMT groups with different doses(30,60,and 90 mg·kg -1 ),propranolol+OMT 60 mg·kg -1 group and doxazosin+OMT 60 mg·kg -1 group. Cannula was cannulated commonly into carotid artery and connected with BL-420 BioLab System to record the blood pressure and heart rate(HR) in rats. Results Mean arterial pressure(MAP) were significantly lower than control in dose-dependent manner after intraventous adminstration of OMT(30,60,and 90 mg·kg -1 ). Conclusion OMT can decrease the MAP in dose-dependent manner. OMT and doxazosin have synergetic effects on MAP." @default.
- W2351104586 created "2016-06-24" @default.
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- W2351104586 date "2005-01-01" @default.
- W2351104586 modified "2023-09-26" @default.
- W2351104586 title "Effects of oxymatrine on blood pressure in rats" @default.
- W2351104586 hasPublicationYear "2005" @default.
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