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- W2351118598 abstract "Objective To investigate the role of Shenqi Fuzheng Injection in rats with (severe acute pancreatitis SAP) and its possible mechanism of myocardial protection. Methods Twenty Six healthy SD rats were randomly divided into 3 groups: K group was given sham operation; M and S groups were established SAP model in rats; S group was treated by intraperitoneal injection of Shenqi Fuzheng Injection after operation. The levels of serum CK-MB ,LDH, Na+-K+ -ATPase activity, mitochondrial membrane potential and myocardial apoptosis were measured after 24 h. Pathologic changes of the pancreas and heart were also detected. Results The levels of serum CK-MB and LDH,the heart pathological scores and the myocardial apoptosis in S group were lower than those in M group (P0.01) but remain higher than those in K group (P0.01),while the Na+-K+ -ATPase activity and mitochondrial membrane potential were higher than those in M group (P0.05) but remained lower than those in control group (P 0.01). Conclusion Shenqi Fuzheng Injection had myocardial protective effect in rats with SAP." @default.
- W2351118598 created "2016-06-24" @default.
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- W2351118598 date "2012-01-01" @default.
- W2351118598 modified "2023-09-28" @default.
- W2351118598 title "Myocardial Protection of Shenqi Fuzheng Injection in Rats with Severe Acute Pancreatitis" @default.
- W2351118598 hasPublicationYear "2012" @default.
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