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- W2351139892 abstract "Objective Observing the osteogenesis of rat bone marrow stromal cells(BMSCs) in osteogenic medium in vitro and in vivo. Methods BMSCs were harvested from rats and induced in control medium (CM) and osteogenic medium (OM). Alkaline phosphatase (ALP) activity assay and von Kossa staining were used to assess the osteogenic differentiation. In vivo OM induced BMSCs were seeded with osteostimulative scaffold PerioGlas and implanted into subcutaneous nude mice to assess the ability of bone formation. Results BMSCs underwent osteogenic differentiation in osteogenic medium, showed higher level of ALP activity and matrix mineralization. Extensive neo-bone formation was observed after 8 weeks of implantation in PerioGlas with OM induced BMSCs. Conclusions BMSCs cultured in osteogenic medium commits to osteoblastic differentiation in vitro and induced ectopic bone formation with PerioGlas in vivo." @default.
- W2351139892 created "2016-06-24" @default.
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- W2351139892 date "2011-01-01" @default.
- W2351139892 modified "2023-09-23" @default.
- W2351139892 title "Osteogenesis of rat bone marrow stromal cells in vitro and in vivo" @default.
- W2351139892 hasPublicationYear "2011" @default.
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