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- W235118328 abstract "Abstract : A series of experiments was done to test the proposition that radiation to the intestine induces prostaglandin production which turn enhances the radiation injury. The results did not support the hypothesis, in that, pharmacologic blockade of prostaglandins or pretreatment with systemic prostaglandins did not significantly alter mortality following abdominal radiation. Neither did prostaglandin manipulations alter hemopoietic suppression. Enteropolling was not induced by abdominal radiation. Systemic pretreatment with free radical inhibitors did not alter mortality following abdominal radiation. Intestinal mucosal integrity was found to be partially preserved by a variety of agents placed in the lumen prior to radiation of isolated intestinal segments. These included prostaglandin E2, cyclooxygenase inhibitors, and adrenal cortical steroids. Keywords: Radiation enteritis; Rat model." @default.
- W235118328 created "2016-06-24" @default.
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- W235118328 date "1987-12-30" @default.
- W235118328 modified "2023-10-16" @default.
- W235118328 title "Prostaglandins and Radiation Enteritis" @default.
- W235118328 doi "https://doi.org/10.21236/ada199250" @default.
- W235118328 hasPublicationYear "1987" @default.
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