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- W2351257436 abstract "The preparation process for o-ethoxy benzoic acid,a key intermediate for sildenafil,was improved with methylsalicylate.The sodium salt of methylsalicylate was firstly prepared and treated with ethyl bromide to give methyl o-ethoxybenzoate,which was hydrolyzed to obtain o-ethoxy benzoic acid(HPLC purity 99.88%).The overall yield was 89.5%.It has been produced in Chongqing Kangerwei phamaceutical Co.Ltd." @default.
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- W2351257436 date "2011-01-01" @default.
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- W2351257436 title "Synthesis of o-Ethoxy Benzoic Acid" @default.
- W2351257436 hasPublicationYear "2011" @default.
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