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- W2351330306 abstract "Objective To investigate the diagnostic significance of telomerase activity in fine-needle puncture cells(FNPC) for malignant and benign disease.Methods The quantitative TRAP-PCR-ELISA was employed to detect telomerose activity of FNPC and biopsy tissue in 82 cases,cytological and pathological diagnosis was made at the same time.Results Telomerase activity in both groups had no signficant difference.Telomerase activity of malignant tumor in FNPC(2.521±0.375) was significantly higher than that of benign tumor(0.057±0.019),and the positive rate was 93.88%(46/49),which was significantly higher than that 6.06%(2/33) of benign tumor.Telomerase activity and its positive rate was higher as the differential level was lower.Telomerase activity of FNPC for diagnosis of malignant tumor had higher positive rate than cytological results.Especially,when cytological results was not typical,thus telomerase activity had more important diagnostic significance.Conclusion Telomerase activity measure of FNPC can be used to differentiate benign and malignant disease." @default.
- W2351330306 created "2016-06-24" @default.
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- W2351330306 date "2000-01-01" @default.
- W2351330306 modified "2023-09-25" @default.
- W2351330306 title "Quantification of Telomerase Activity in Fine-needle Puncture Cell" @default.
- W2351330306 hasPublicationYear "2000" @default.
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