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- W2351453314 abstract "Objective To observe the effect of Shugan xiaozhi capsules(SXC) on hepatic cytochrome P4502E1(CYP2E1) of non-alcoholic fatty liver rats.Methods The animal model of non-alcoholic fatty liver disease(NAFLD) was established with a high-fat emulsion for seven weeks.The hyperlipidemia in rats was developed at 3rd week,and rats then were treated with SXC or compound methionine choline tablet for four weeks.Pathological changes and hepatic CYP2E1 were measured.Results Compared with the model group,the hepatic CYP2E1 content and hepatocellular fatty degeneration were significantly decreased in the SXC-treated group(P 0.01).Conclusion SXC could effectively reduce the liver tissue CYP2E1,which may be related to prevention and treatment of NAFLD." @default.
- W2351453314 created "2016-06-24" @default.
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- W2351453314 date "2013-01-01" @default.
- W2351453314 modified "2023-09-23" @default.
- W2351453314 title "Effect of Shugan xiaozhi capsules on hepatic cytochrome P450-2E1 of non-alcoholic fatty liver rats" @default.
- W2351453314 hasPublicationYear "2013" @default.
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