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- W2351608082 abstract "Objective:To observe the stability of thymosin α_1 microspheres under preparation conditions.Methods: Using HPLC method,we investigated the influence of different temperatures(-20 ℃, 6-8℃,60℃),sonification time(10-60 s) and pH values (pH 4.0,7.0 and 10.0) on thymosin α_1 stability.Results: Under the conditions of frozen environment(-20℃) and refrigeration(6-8℃), thymosin α_1 remained stable for 30 d.Thymosin α_1 did not degrade in 60℃ water bath for 12 h or in phosphate buffer solution(PBS,pH 4.0) under 37℃ for 14 h.The sonification time within 60 s was found to be safe for the preparation.Conclusion: Thymosin α_1 is stable under these preparation conditions." @default.
- W2351608082 created "2016-06-24" @default.
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- W2351608082 date "2005-01-01" @default.
- W2351608082 modified "2023-09-28" @default.
- W2351608082 title "Stability evaluation of thymosin α_1 under microsphere preparation condition" @default.
- W2351608082 hasPublicationYear "2005" @default.
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