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- W2351615667 abstract "Objective To study passive cutaneous anaphylaxis(PCA) of Qingzi Keli. Methods Sixty 15~17g and ten 30g KM mice were used. Each 30g mice was injected with trichosanthin and aluminium hydroxide to get the standby serum. Sixty 15~17g mice were divided into test groups with fifty mice and blank drug group with ten mice. The test group mice were randomly distributed into five groups: model control group, high dose of Qingzi granules group, middle dose of Qingzi granules group, low dose of Qingzi granules group and chlorphenamine maleate group. After continuous intragastric administration of physiological saline group and corresponding drug for 7d,mice were injected trichosanthin 24mg/kg and killed respectively. Inhibitory effect of PCA in six groups were measured by blue-spot'area and colorimetric analysis. Results High, middle and low dose Qingzi granules could inhibit PCA in mice, the effect of high-dose Qingzi granules and chlorphenamine maleate were stronger than that of middle and low-dose Qingzi granules. Conclusions Qingzi Keli showed a significant inhibition on passive cutaneous anaphylaxis ( PCA ). It indicates Qingzi Keli has obvious antianaphylaxis effect." @default.
- W2351615667 created "2016-06-24" @default.
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- W2351615667 date "2010-01-01" @default.
- W2351615667 modified "2023-10-17" @default.
- W2351615667 title "Effect of Qingzi Keli on passive cutaneous anaphylaxis in mice" @default.
- W2351615667 hasPublicationYear "2010" @default.
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