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- W2351675985 abstract "Objective: To investigate the effects of Cong Sheng capsule (CSC) on learning memory ability in rats and membrane integrality of cultured neurons after ischemia reperfusion. Methods The step down test and water maze test were measured to study the learning memory ability in the model rats produced by bilateral carotid artery occlusion and reperfusion combined with a lowing of mean artery blood pressure by bleeding. Using drug serum to study the action of CSC on neuronal damage during hypoxia 3 h /reoxygenation (0,3,6,18 h) which was reflected by the release of lactate dehydrogenase (LDH) from cells into culture medium. Results CSC 1.5 g and 3 g/kg i.g. improved the learning and memorizing impairment of model rats. The serum preparation of CSC (2,4,8g/kg) attenuated neuronal damage during hypoxia 3 h / reoxygenation (0,3,6,18 h) by decreasing LDH release. Conclusion The CSC has protective effect on cerebral ischemic damage." @default.
- W2351675985 created "2016-06-24" @default.
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- W2351675985 date "2003-01-01" @default.
- W2351675985 modified "2023-09-25" @default.
- W2351675985 title "Effect of cong-sheng capsule on learning-memory activity in rats and membrane integrality of cultured neurons after ischemia-reperfusion" @default.
- W2351675985 hasPublicationYear "2003" @default.
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