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- W2351685846 abstract "Objective To prepare Uben-CS-NP and evaluate its quality with modern science and technology. Methods Uben-CS-NP was prepared by Ionic Cross-linking method, and its form, size, zeta potential, pH, entrapment efficiency, drug loading and drug release were evaluated. Results The preparation method for Uben-CS-NP was feasible. The form was round, with particle size 300-600 nm(averagely 442 nm). Zeta potential was + 37.8 mV, pH was 6.0, entrapment efficiency was 69.1%, and drug loading was 31.4%. Drug release in vitro: the cumulative dose quickly reached 28.77% at 1 h, and then released slowly. At 12 h and 24 h, the cumulative dose was 42.56% and 50.93%. Conclusion The quality of Uben-CS-NP can be controlled. In vitro drug release behavior conforms to Higuchi equation, and Uben-CS-NP has obvious sustained release effect." @default.
- W2351685846 created "2016-06-24" @default.
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- W2351685846 date "2014-01-01" @default.
- W2351685846 modified "2023-09-23" @default.
- W2351685846 title "Preparation and quality evaluation of Uben-CS-NP" @default.
- W2351685846 hasPublicationYear "2014" @default.
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