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- W2351736100 abstract "Objective In order to predict combined B-and T-cell epitopes,the protein secondary structure of the Em95 antigen was analyzed using related software and the Internet.Methods To look for the common regions of B-and T-cell epitopes of Em9,the B-and T-cell epitopes of Em95 were predicted using DNAStar and IEDB,SYFPEITHI,and Propred online.Results Em95 has many latent antigenic epitopes.The possible B cell epitopes of Em95 are in the regions of 10-19,43-48,52-59,78-82,92-100,and 110-115.High-scoring T-cell epitopes are in the regions of 32-40,51-60,82-98,108-116,and 126-138.The common regions of B-and T-cell epitopes of Em95 are 52-59,92-98,and 110-115.Conclusion Bioinformatics indicated that there are three combined B-and T-cell epitopes in Em95,with 6 B-cell antigenic epitopes and 5 T-cell antigenic epitopes.These results are vital to further research on the antigenic characteristics and development of vaccines containing the dominant epitopes of Em95." @default.
- W2351736100 created "2016-06-24" @default.
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- W2351736100 date "2012-01-01" @default.
- W2351736100 modified "2023-09-22" @default.
- W2351736100 title "Analysis of combined T-and B-cell epitopes of the Em95 antigen of Echinococcus multilocularis" @default.
- W2351736100 hasPublicationYear "2012" @default.
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