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- W2351743960 abstract "Objective To investigate the RBC parameters and the serum levels of IL-6,IL-17 and IL-18,and further to explore the influence of levels of IL-6,IL-17 and IL-18 on the pathogenesis of anemia in the patients with hepatitis B-related cirrhosis.Methods The RBC parameters were detected in 114 patients with hepatitis B-related cirrhosis and 30 healthy people as control group respectively.And the levels of serum IL-6,IL-17 and IL-18 were detected with ELISA in both groups.Results The levels of RBC,Hb and Hct were significantly decreased,and RDW were significantly increased in the hepatitis B-related cirrhosis group than those in the healthy control group(P0.05).There was no statistical difference in MCV between the two groups(P0.05).The levels of serum IL-6,IL-17 and IL-18 in the hepatitis B-related cirrhosis group were significantly increased compared with the healthy control group(P0.05).And there was negative relationship between serum levels of IL-6,IL-17 and IL-18 with the level of Hb in the hepatitis B-related cirrhosis group(P0.05).Conclusion Cytokines IL-6,IL-17 and IL-18 play an important role in the pathogenesis of anemia resulted from hepatitis B-related cirrhosis." @default.
- W2351743960 created "2016-06-24" @default.
- W2351743960 creator A5084692553 @default.
- W2351743960 date "2013-01-01" @default.
- W2351743960 modified "2023-09-23" @default.
- W2351743960 title "Analysis of RBC parameters and associated cytokines detection in patients with hepatitis B-related cirrhosis" @default.
- W2351743960 hasPublicationYear "2013" @default.
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