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- W2351775481 abstract "OBJECTIVE To study the effect of lycopene on treatment of murine load H22 with 5-Fu.METHODS The effect was tested by using transplanted solid and ascetic load H22 model.The toxicity caused by 5-Fu was examined by peripheral blood cells counting、clearance rate of charcoal particles、delayed type hypersensitivity、serum content of agglutinin and IL-2 as well as IF-γ.RESULTS Lycopene had a synergistic antitumor activity with 5-Fu in both solid and ascitic tumor models(P0.01),meanwhile,it protected sarcoma mice treated with 5-Fu against decreasing in marrow cell and peripheral blood cell counts、clearance rate of charcoal particles、delayed type hypersensitivity、serum content of agglutinin and IL-2 as well as IF-γ.CONCLUSION Lycopene could enhance therapeutic effect and decrease toxicity on treatment of 5-Fu for murine load H22." @default.
- W2351775481 created "2016-06-24" @default.
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- W2351775481 date "2009-01-01" @default.
- W2351775481 modified "2023-09-23" @default.
- W2351775481 title "Cooperative effect of lycopene on murine load H_(22) treatment with 5-fluorouracil" @default.
- W2351775481 hasPublicationYear "2009" @default.
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