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- W2351794737 abstract "Objective To establish the nude mice model of lymphatic metastasis using tongue squamous cell carcinomal(TSCC) Tca8113 cell line.Methods The lymphatic metastasis nude mice models were established by injecting Tca8113 cells into the nail pad,lymph nodes were collected after 4 weeks.The detection include the HE strain,immunohistochemistry strain of EMA and CK18 proteins and the purification and culture of tongue squamous cell carcinoma cells in vitro.Results The lymphatic metastasis rate was 67.5%(23/35).There are EMA and CK18 proteins expression and lymphatic metastasis carcinomal cells in the lymph node of nude mice of TSCC metastasis model.In purification and culture,the cells of epithelium like growth were observed in vitro.Conclusion Injecting Tca8113 cells into the nail pad can establish the lymphatic metastasis model.The model was regarded as basis study of the lymphatic metastasis mechanisms and the research of anti-lymphatic metastasis drug." @default.
- W2351794737 created "2016-06-24" @default.
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- W2351794737 date "2006-01-01" @default.
- W2351794737 modified "2023-09-23" @default.
- W2351794737 title "Establishment of the tongue squamous cell carcinoma lymphatic metastasis model of the nude mouse" @default.
- W2351794737 hasPublicationYear "2006" @default.
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