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- W2351842294 abstract "Objective:To observe expressions of AQP1 in and kidney tissues and contents of ET、IL-1β、TNF-α in blood in Lung-Qi deficiency model rats.The aim was to provide experimental evidence for traditional Chinese medical theory of the kidney is related with in charge of regulating water passage.Methods:The rats of lung-Qi deficiency were simulated by injecting lipopolysaccharide into trachea with cigarette smoking.Immunohistochemistry and Western blot analysis were used to observe expression of AQP1;RT-PCR was applied to analyze expression of AQP1 mRNA in and kidney tissues.Blood sample was taken and concentrations of ET,IL-1β,TNF-α were measured by radioimmunoassay.Results:AQP1 expression in tissue in model group was obviously lower than that in control group,and so was AQP1 mRNA.AQP1 expression in kidney tissue in control group was greater than that in control group,and so was AQP1 mRNA(P0.01).ET,IL-1β,TNF-α concentrations of blood in model group were markedly higher than those in control group(P0.01).Conclusion:In Lung-Qi deficiency model rats,AQP1 expression down regulated in tissue.AQP1 expressions increased in kidney tissue.Concentrations of ET,IL-1β and TNF-α increased obviously in blood.One of substance basis of lung is upper source of watermay be AQP1 retro-expression in and kidney tissues." @default.
- W2351842294 created "2016-06-24" @default.
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- W2351842294 date "2012-01-01" @default.
- W2351842294 modified "2023-09-24" @default.
- W2351842294 title "Water Metabolism Correlation Study of Lung and Kidney Tissues in Lung-Qi Deficiency Model Rats" @default.
- W2351842294 hasPublicationYear "2012" @default.
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