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- W2351844894 abstract "Objective: To explore the relationship between maternal mental health status during early pregnancy and birth defects. Methods: A case-control study was conducted. Symptom check list(SCL-90) was administered to 635 cases (mothers of fetus with birth defects) and 1263 controls (mothers of normal fetus) to evaluate their mental health status in early stage of pregnancy. Results: The detection rate of mild and moderate mental problems in the case group was 12.28% and 1.73% respectively, which were significantly higher than those in the control group (8.00% and 0.71%); the positive rates of interpersonal sensitivity, depression, hostility, paranoid ideation and psychoticism symptoms were also significantly higher in the case group than those in the control group. After controlling factors, such as pregnant women’s age, nation, educational level, occupation and living place, those with mild mental problems would increase 1.60 times risk of birth defects in their fetus than the control group in Logistic regression models. Further analysis showed that women with positive interpersonal sensitivity, hostility, paranoid ideation, psychoticism symptoms during early pregnancy may increase fetus’ risk of birth defects (ORs:1.68,1.82,1.96,4.20 respectively). Conclusion: Maternal mental health status during early pregnancy is related to fetus’ risk of birth defects." @default.
- W2351844894 created "2016-06-24" @default.
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- W2351844894 date "2009-01-01" @default.
- W2351844894 modified "2023-09-23" @default.
- W2351844894 title "A Case-control Study on Relationship Between Maternal Mental Health Status During Early Pregnancy and Birth Defects" @default.
- W2351844894 hasPublicationYear "2009" @default.
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