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- W2351889669 abstract "The recombinant strains BL21(pFSFaeG) and X4550(pFSFaeG),which expressed protective antigens of porcine pathogenic Escherichia coli,and activity of toxin was lost completely were constructed.The 5-week-old mice were immunized with live recombinant bacteria orally and with inactivated vaccine by the peritoneal route.Sera and feces were simultaneously collected from the vaccined mice on the 7,14 d post both the first and second immunization.The result indicated that serum IgG specific to F4,F18 and Stx 2e antigens could be stimulated in mice immunized with inactivated vaccine,but could not in all oral groups.The protection efficacy of mice immunized with inactivated recombinant strain against challenging of strain 107/86,C83907 and Stx 2e was much better than mice immunized with live recombinant bacteria orally." @default.
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- W2351889669 date "2005-01-01" @default.
- W2351889669 modified "2023-09-23" @default.
- W2351889669 title "Immune efficacy of two recombinant strains expressing the major protective antigens of porcine pathogenic Escherichia coli caused postweaning diarrhoea and edema disease" @default.
- W2351889669 hasPublicationYear "2005" @default.
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