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- W2351895384 abstract "Objective To explore the role of elastin in experimental fatty liver and liver and liver fibrosis. Methods Experimental liver fibrosis rats models of were induced by high fat diet, low fat diet plus ethanol, high fat diet plus ethanol, and carbon tetrachloride subcutaneous injection, respectively. At sacrifice the followings were evaluated, liver pathologic changes and elastin expression by immunohistochendstry using a monoclonal antibody. Results Expression of elastin was not observed in the models of low fat diet, high fat diet and low fat diet plus ethanol, but was seen a few in high fat diet plus ethanol and all in carbon tetrachloride. The intensity of elastin expression is more obvious in the hepatic perisinusoidal cells than hepatocytes. Conclusions In the course of fatty liver and liver fibrogenesis, elastin expression was found in the late stage of liver fibrosis, reflected the disease-process of liver fibrosis. Hepatic perisinuous cells, especially HSCs, played an important role in the liver fibrogenesis." @default.
- W2351895384 created "2016-06-24" @default.
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- W2351895384 date "1999-01-01" @default.
- W2351895384 modified "2023-10-15" @default.
- W2351895384 title "Expression of elastin in experimentsl fatty liver and liver fibrosis" @default.
- W2351895384 hasPublicationYear "1999" @default.
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