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- W2351917278 abstract "Objective To observe the effect of ligustrazine and shenmai injection on pulmonary artery hypertension(PAH) in cor pulmonale.Methods 100 patients of chronic cor pulmonale in acute stage with cardiac function class Ⅲ~Ⅳ on NYHA were randomly divided into control group and treatment group.The two groups were received routine therapy,but the treatment group was treated by ligustrazine and shenmai injection in addition.To observe symptoms,signs,sPAP,LVEF,systemic BP,6-MWT and adverse drug reactions in the two groups.Results The obvious effective rate,total effective rate,PAH depressed rate,LVEF increased rate and 6-MWT increased level of control group was respectively 40%,84%,17.83%,8.08% and 1.4.The treatment group was respectively 80%,98%,27.04%,10.36% and 2.1.There was statistical significance on items between the two groups(P0.05).Conclusion Ligustrazine and shenmai injection may reduce pulmonary hypertension and reverse pathological change on pulmonary vascular.It couldn′t reduce blood pressure and CO.The result shows that it is a operative and economical method for patients on chronic cor pulmonale in acute stage." @default.
- W2351917278 created "2016-06-24" @default.
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- W2351917278 date "2012-01-01" @default.
- W2351917278 modified "2023-09-23" @default.
- W2351917278 title "Effect of Ligustrazine and Shenmai Injection on Pulmonary Artery Hypertension in Cor Pulmonale" @default.
- W2351917278 hasPublicationYear "2012" @default.
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