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- W2351938495 abstract "Purpose To explore the clinicopathological characteristics, differential diagnosis, and its immunohistochemical expression of high grade astroblastoma. Methods One case of high grade astroblastoma was reported, with review of relevant literature. Results One case of high grade astroblastoma is a well-circumscribed, nodular and cystic change. Histological features were characterized by a typical perivascular pseudorosettes pattern of tumor cells with broad, non-tapering processes radiating towards a central blood vessel and cellularity with multiple cell layers piled upon the vascular walls, cellular atypia, high mitotic rate without significant hyalinization of the vascular walls. Conclusions Astroblastoma is one of the very unusual type of tumors, whose histogenesis has not been clarified. Astroblastomas are classified into low grade and high grade according to histological features and supposed to be distinguished from other neuroepithelial neoplasms. The so-called low-grade astroblastomas are thought to have better prognosis than those with high-grade histological features. In addition, low-grade astroblastomas have long-term survival for gross total removal. Adjuvant therapy (radiotherapy and/or chemotherapy) can be considered in high-grade astroblastomas, with a close follow-up for all cases." @default.
- W2351938495 created "2016-06-24" @default.
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- W2351938495 date "2008-01-01" @default.
- W2351938495 modified "2023-09-23" @default.
- W2351938495 title "Clinicopathologic features of high grade astroblastoma:a case report and the review of the literatures" @default.
- W2351938495 hasPublicationYear "2008" @default.
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