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- W2351973334 abstract "Objective To study on the feature of CYP2C9*1,CYP2C9*2,CYP2C9*3 genetic polymorphisms of cytochrome P450(CYP2C9)in patients with warfarin anticoagulant therapy in Shenzhen area.Methods The CYP2C9*1,CYP2C9*2,CYP2C9*3 genetic polymorphisms of cytochrome P450(CYP2C9)were analyzed in 151 patients with warfarin anticoagulant therapy by polymerase chain reaction and restriction fragment length polymorphism(PCR-RFLP).Results There were no CYP2C9*2 allele in 151 patients with warfarin anticoagulant therapy .The allele frequencies of CYP2C9*1,CYP2C9*3 were 92.7% and 7.3% respectively.The genotype frequencies of CYP2C9*1*1,CYP2C9*1*3,CYP2C9*3*3 were 85.4%(129),14.6%(22),0(0)respectively.Conclusion The CYP2C9*3 mutant is present in patients with warfarin anticoagulant therapy in Shenzhen area.CYP2C9 genotype should be analyzed when using warfarin anticoagulant therapy." @default.
- W2351973334 created "2016-06-24" @default.
- W2351973334 creator A5077283085 @default.
- W2351973334 date "2008-01-01" @default.
- W2351973334 modified "2023-09-23" @default.
- W2351973334 title "STUDY ON THE GENETIC POLYMORPHISM OF CYTOCHROME P450(CYP2C9)IN PATIENTS WITH WARFARIN ANTICOAGULANT THERAPY" @default.
- W2351973334 hasPublicationYear "2008" @default.
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