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- W2351998966 abstract "Objective To assess early changes in pulmonary function of patients with lung cancer after intensity modulation radiation therapy(IMRT).To perform a preliminary evaluation of the possibility of using pulmonary perfusion imaging to select the beam arrangement.Methods 30 lung cancer patients received the pulmonary perfusion imaging and PFTs(pulmonary function tests) before and after IMRT.Based on pre-IMRT pulmonary perfusion images,the patients were divided into 3 groups.pre-IMRT pulmonary perfusion images were used to guide the beam arrangement in IMRT planning.The results were analyzed with the matched t test.And then all patients were divided into 2 groups according to whether they were treated with concurrent chemoradiotherapy or not.The aim was to investigate the effects of medication on pulmonary function.Result There was significant difference in VC and TLCO-SB in the group that pre-PFTs were normal.Other indexes were not significantly different.All indexes of other two groups had no significant difference.There was significant difference in TLCO-SB in the group with concurrent chemoradiotherapy.Conclusion Using pulmonary perfusion images to guide the beam arrangement in IMRT planning is good for the decrease of radiation induced lung injury.The early pulmonary function injury of IMRT appears in vital capacity.Concurrent chemoradiotherapy can aggravate the injury of pulmonary diffusion function." @default.
- W2351998966 created "2016-06-24" @default.
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- W2351998966 date "2011-01-01" @default.
- W2351998966 modified "2023-09-27" @default.
- W2351998966 title "Assessing Radiation Injury on Patients with Lung Cancer by the Changes of Ventilation and Perfusion" @default.
- W2351998966 hasPublicationYear "2011" @default.
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