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- W2352000136 abstract "Objective To compare the metabolic changes in transient ischemic attacks(TIA) and cerebral infarction by 1 H magnetic resonance spectroscopy (1H-MRS), and to explore the value of 1 H-MRS on TIA. Materials and Methods 1H-MRS were performed in 30 patients with TIA and 24 with infarction and 24 control subjects. Cerebral metabolism was studied by assessing peak areas of N acetyl aspartate (NAA), choline (Cho) and creatine (Cr) as well as peak height ratio of lactate(Lac) to Cr on the both sides. Results In TIA patients, decreased NAA and increased Cho were found in the symptomatic centrum semiovale compared with the asymptomatic side and the control subjects (P0.01). The concentrations of Cr had no obvious changes (P0.05). In cerebral infarction patients, the concentrations of NAA, Cho and Cr were all significantly decreased in the lesion compared with the contralateral noninfarcted areas and the control subjects (P0.01). But NAA did not decrease in TIA as severely as that in infarction(P0.01). Lac was observed in 10 TIA patients and 23 cerebral infarction patients. The Lac/Cr ratio of the TIA patients was lower than that of the cerebral infarction patients (P0.01). Conclusion The abnormal metabolic changes could be found in TIA, but were not as severe as those in cerebral infarction. 1 H-MRS could provide valuable information about metabolic changes in TIA and play an important role in the diagnosis and treatment of TIA." @default.
- W2352000136 created "2016-06-24" @default.
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- W2352000136 date "2007-01-01" @default.
- W2352000136 modified "2023-09-28" @default.
- W2352000136 title "Comparative Study of ~1H-MR Spectroscopy in Transient Ischemic Attacks and Cerebral Infarction" @default.
- W2352000136 hasPublicationYear "2007" @default.
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