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- W2352012783 abstract "Objective: To explore the protective effects of salvia miltiorrhiza for enteral nutrition on the gut function in rabbits. Methods: Fortyfour 10week old rabbits were randomly divided into normal control group, lipopolysaccharide(LPS) group, salvia miltiorrhiza for enteral nutrition group and nutrition fibre (group(DS)). The experiment period was 10 days. At the end of experiment, the body weight, plasma (albumin), the superoxide dismutase(SOD) activity and malondialdehyde(MDA) content, endotoxin level and secretory immunoglobubin A(sIgA) in small intestine mucosa and lymphocyte DNA damage were measured. (Results): The serum endotoxin level in salvia miltiorrhiza for enteral nutrition group was (0.53±0.24) EkU/L, it was significantly lower than that of LPS group (2.33±0.41)EkU/L (P0.01); the contents of sIgA ((1.64±0.65)) had a increasing trend compared with LPS group (1.25±0.29); the serum MDA level was ((0.532±0.197)μmol/L), it was significantly decreased than that of control group(0.890±0.051)μmol/L((P0.01)); the DNA shift distance was markedly reduced than LPS group(P0.01). Conclusion: Salvia (miltiorrhiza) for enteral nutrition could prevent gut function damage, protect intestinal mucosa, maintain the (intestinal) barrier function by reducing the oxidative damage and decreasing the LPS translocation." @default.
- W2352012783 created "2016-06-24" @default.
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- W2352012783 date "2004-01-01" @default.
- W2352012783 modified "2023-09-27" @default.
- W2352012783 title "Protective effects of salvia miltiorrhiza for enteral nutrition on the gut function in endotoxemia rabbits" @default.
- W2352012783 hasPublicationYear "2004" @default.
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