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- W2352012957 abstract "OBJECTIVE The inhibitory effects of quercetin, kaempferol,myricetin and rutin from Carthamus tinctorious L.against rabbit polymorphonuclear leucocyte (PMN) aggregation and adhesion induced by platelet activating factor(PAF) were studied.METHOD Rabbit PMN was prepared through gelatin precipitation procedure.After induced by PAF, PMN aggregation was observed by turbidity assay.Coloured PMN, which was activated by PAF and adhered to the surface of plastics, was broken and the A 570 nm of the solution was measured to show the adhesion potency.RESULTS The aggregation rate and A 570 nm were decreased evidently ( P 0.05) after treated with above flavonols. The IC 50 of quercetin, kaempferol, myricetin and rutin in aggregation test were 0.728,0.542,0.104 and 4.45 mmol·L -1 respectively.CONCLUSION It was suggested that the inhibitory effects against PMN aggregation and adhesion induced by PAF of these flavonols were dose dependent." @default.
- W2352012957 created "2016-06-24" @default.
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- W2352012957 date "2002-01-01" @default.
- W2352012957 modified "2023-09-23" @default.
- W2352012957 title "Inhibitory effects of some flavonols from Carthamus tinctorious against polymorphonuclear leucocyte aggregation and adhesion induced by platelet activating factor" @default.
- W2352012957 hasPublicationYear "2002" @default.
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