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- W2352021071 abstract "Objective To reveal the changes of pre- and post-prandial sigmoid colon motility in patients with irritable bowel syndrome. Methods 20 consitipation-predominant and sex/age mathched 20 diarrhea-predominant IBS patients and 15 healthy volunteers were enrolled in the experiment. Migrating and nonmigrating long spike bursts and motor index were recorded before and after a test meal by a water perfusing manometry apparatus connected with a computer.Result In fasting status, diarrhea-predominant IBS patients had higher motor index mainly due to the elevated wave amplitude and the percent of the recording time of the migrating long spike bursts, The test meal significantly increased the amplitude and the number of migrating and nonmigrating long spike bursts in all subjects,especially in the volunteers in the first half hour. The gastrocolic reflex of the diarrhea-predominant IBS patients lasted longer than that of the consitipation-predominant IBS patients and healthy subjects mainly owed to increased amplitude of migrating long spike bursts and the number of nonmigrating long spike bursts. Conlusion Diarrhea-predominant IBS patients have stronger sigmoid colon motility in fasting state; The gastrosigmoidocolic reflex appears earlier in healthy subjects than in IBS patients and it lasts longer in diarrhea-predominant IBS patients than in consitipation-predominant IBS patients and healthy subjects." @default.
- W2352021071 created "2016-06-24" @default.
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- W2352021071 date "2004-01-01" @default.
- W2352021071 modified "2023-09-25" @default.
- W2352021071 title "The study of sigmoid colon motility in patients with irritable bowel syndrome" @default.
- W2352021071 hasPublicationYear "2004" @default.
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