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- W2352054661 abstract "Objective To evaluate effecacy of amoxicillin and amoxicillin dicloxacillin sodium for the eradication of H.pylori.Methods Totally 155 helicobaeter pylori-infected patients with peptic ulcer diagnosed by endoscopy were enrolled.The patients were randomly divided into three groups,and drugs were given as follows: each of the 52 patients of group A was given lansoprazole 30 mg+amoxicillm 1.0 g+tinidazole 0.5 g;each of the 51 patients of group B was given lansoprazole 30 mg+amoxicillin dicloxacillin sodium 0.75 g+tinidazole 0.5 g;each of the 52 patients of group C was given lansoprazole 30 mg+amoxicillin dicloxacillin sodium 1.5 g+ tinidazole 0.5 g.All drugs were given twice a day for seven days.After finishing of H.pylori therapy at least four weeks,and after withdrawing of PPI at least two weeks,we compared the H.pylori status,ulcer healing,and side-effects among three groups by inquisition,endosecopy and 13C breathing test.Results There was significant difference of the H.pylori eradication rate among the three groups(P0.05).The results between group A and group B were significantly different(P0.0167).The results between group A and group C was no significant difference,either was the results between group B and group C. The healing rates of peptic ulcer were no significant difference(P0.05) among the three groups.There was significant difference among the three groups(P0.05).The results between group A and group B were significantly different(P0.0167).The results between group A and group C were not significantly different,either were the results between group B and group C.The rate of ADR showed no significant difference among the three groups.Conclusion Comparison of three groups,amoxicillin,which has highest H.pylori eradication rate,highest ulcerative healing,lowest incidence of ADR,is better than amoxicillin dicloxacillin sodium as an antibiotics for H.pylori eradication." @default.
- W2352054661 created "2016-06-24" @default.
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- W2352054661 date "2013-01-01" @default.
- W2352054661 modified "2023-09-25" @default.
- W2352054661 title "The comparative study of amoxicillin and amoxicillin dicloxacillin sodium for the eradication of H.pylori" @default.
- W2352054661 hasPublicationYear "2013" @default.
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