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- W2352062720 abstract "Objective: To investigate the influence of diabetes mellitus and insulin therapy on treatment outcomes in patients with nasopharyngeal cancer.Methods: We summarized 86 patients diagnosed as having diabetes and nasopharyngeal cancer,treated by radiotherapy between January 1999 and December 2002,with a median follow-up of 50.1 months.We analyzed the OS,RFS,MFS and DFS.Furthermore,the affect of chemotherapy and insulin therapy on long-term outcomes were investigated.Results: The OS of 86 patients was 47.7%,DFS 40.7%,RFS 43.0% and MFS45.4%.OS of chemotherapy group was 48.6% vs 46.9% of non-chemotherapy group(P0.05).There was no significant difference between induction and concurrent chemotherapy groups(P0.05).For patients diagnosed as advanced stage,OS of chemotherapy group was 45.7% vs 23.5% in non-chemotherapy group(P0.05).27(31.4%) patients received insulin therapy,OS,RFS,MFS of insulin group was 33.3%,33.3%,33.3% vs 54.2%,47.5%,50.8% in non-insulin group(P0.05).Among 37 patients received chemotherapy,14 had insulin therapy.OS of insulin group was 28.6% vs 60.9% of non-insulin group in chemotherapy patients(P0.05).Conclusion: hemotherapy didn't have advantages in nasopharyngeal cancer patients with diabetes.Insulin therapy had adverse affect on long-term survival in nasopharyngeal cancer patients." @default.
- W2352062720 created "2016-06-24" @default.
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- W2352062720 date "2009-01-01" @default.
- W2352062720 modified "2023-09-24" @default.
- W2352062720 title "Association of diabetes mellitus and treatment outcomes in patients with nasopharyngeal cancer" @default.
- W2352062720 hasPublicationYear "2009" @default.
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