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- W2352109746 abstract "Objective To explore a new drug to treat the injury of cerebral ischemia and reperfusion.Methods Seventy-two Sprague-Dawley(SD) rats were randomly divided into 3 groups: physiological saline group,1 mg Edaravone group and 0.5 mg Edaravone group.Then they were both divided into 3 sub-groups(1 h,6 h,24 h).Then made the local cerebral ischemic reperfusion model with thread embolism of right middle cerebral artery(MCA) in male SD rats.Edaravone was dissolved in physiological saline and injected intravenuously in the model of SD rats.Cerebral infarct volumes were calculated with computer tomography after a week.Results Edaravone was able to effectively reduce infarct volumes in brains after male SD rats ischemia and reperfusion.Conclusion Edaravone can effectively protect brain after cerebral ischemia so as to treat local reperfusion injury." @default.
- W2352109746 created "2016-06-24" @default.
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- W2352109746 date "2006-01-01" @default.
- W2352109746 modified "2023-09-22" @default.
- W2352109746 title "Exploration of Effect after Cerebral Ischemia with Edaravone" @default.
- W2352109746 hasPublicationYear "2006" @default.
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