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- W2352173090 abstract "Objective To investigate the gentamycin resistance genotype and phenotype among the clinical isolates of Staphylococcus haemolyticus(S.haemolyticus).Methods Agar dilution method was performed to detect the minimal inhibition concentrations(MIC) of oxacillin,gentamycin and other five antimicrobial agents against 63 strains of S.haemolyticus,and the resistance genes of mecA and aac(6′)-aph(2″) were investigated by polymerase chain reaction(PCR) in all clinical isolates.Results 74.6% of isolates were resistant to gentamycin,with the MIC50of 64 μg/mL and MIC90 of 128 μg/mL.Methicillin-resistant S.haemolyticus(MRSH) non-susceptible to gentamycin showed higher resistance rates to cipfloxacin and erythromycin than gentamycin-susceptible MRSH(85.7% and 87.8% vs 0% and 46.2%,respectively,P0.005).13 gentamycin-susceptible isolates were not found having aac(6′)-aph(2″) gene,while this gene was detected in 50 isolates non-susceptible to gentamycin(MIC 8-≥128 μg/mL),and 49 strains among them carried also mecA gene.Conclusions aac(6′)-aph(2″) gene plays a major part in S.haemolyticus resistant to gentamycin." @default.
- W2352173090 created "2016-06-24" @default.
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- W2352173090 date "2008-01-01" @default.
- W2352173090 modified "2023-09-26" @default.
- W2352173090 title "Investigaton of gentamycin resistance genotype and phenotype in Staphylococcus haemolyticus" @default.
- W2352173090 hasPublicationYear "2008" @default.
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