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- W2352202277 abstract "Objective To discuss the clinical characteristic and drug susceptibility of nosocomial fungus infection of severe hepatitis patients. Methods 150 hospitalized cases of severe hepatitis patients with nosocomial fungus infection were investigated and analyzed retrospectively. Results Fungus infection of upper respiratory tract accounted for 45.33%, infection rates in lower respiratory tract, intestinal tract, abdominal cavity and bile duct were 23.33%, 21.33%, 20.00%, and 18.67%, respectively. Candida albicans accounted for 50.67% and Albicans tropicals for 18.87%. The susceptibility to seven antibiotics: the susceptibility rates of all fungi to amophotericin were about 90%, and to fluconazole were about 80%. All the fungi showed certain degree of resistance to enconazole, ketoconazole, itraconazole, and miconazole. The resistance rates of all fungi to nystatin were 70%. The mortality of patients co-infected by two strain bacteria was 80%, and it was higher than that by one strain bacterium (P 0.01). Use of broad-spectrum antibiotic, neutropenia, improper medical manipulations and severity of liver disease were risk factors of fungus infection (P 0.01). Conclusion The mortality of severe hepatitis patients with nosocomial fungus infection coinfected by bacteria was very high. All the fungi showed certain degree of resistance to routinely used antibiotics. Comprehensive measures must be administrated to prevent and treat nosocomial fungus infection." @default.
- W2352202277 created "2016-06-24" @default.
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- W2352202277 date "2005-01-01" @default.
- W2352202277 modified "2023-09-25" @default.
- W2352202277 title "The Clinical Characteristic and Drug Susceptibility of Nosocomial Fungus Infection of Severe Hepatitis Patients" @default.
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