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- W2352202407 abstract "Recent research suggests that the serum procollagen type Ⅲ (PC Ⅲ )could be a good marker in the diagnosis of hepatic fibrosis. Radioimmunoassay is mostly used in its determination and the antigen is isolated from fetal skin of animals. In this report PC Ⅲ was isolated and purified from human fetal skin of induced abortion. The characteristic of this antigen was successfully identified. There was only one band on PAGE;Two bands namely pro α1(Ⅲ)and p α1( Ⅲ )were presented after reduction, the mplecular weight of former was 190 000 and later 1700 000; The high value of anti-serum was acquired from rabbit after immunization; Collagen fibers of biopsies with cirrhosis and chronic active hepatitis were stained with brown colour on immunohistochemistry. So far there is no report about the isolation of PC Ⅲ from human source. The antigenicity of human PC Ⅲ is somewhat different from that of animals,therefore the antigen isolated from human source would be more satisfactory." @default.
- W2352202407 created "2016-06-24" @default.
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- W2352202407 date "1992-01-01" @default.
- W2352202407 modified "2023-09-28" @default.
- W2352202407 title "ISOLATION AND PURIFICATION OF HUMAN PROCOLLAGEN TYPE III AND PREPARATION OF ITS ANTISERUM" @default.
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