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- W2352207029 abstract "Objective: To investigate the correlation between the eNOS G894T polymorphism and the presence and severity of coronary heart disease (CHD) in Dongxiang ethnic minority.Methods: All patients were selected from the Dongxiang ethnic minority ,including CHD patient 203 examples in which the severity of CHD was expressed by the number of affected vessels and the normal group 194 examples by coronary angiograms.The polymerase chain reaction -restriction fragment length polymorphism analysis(PCR-RFLP) was used to detect the genetype in G894T variant of the eNOS gene in both samples.Results: The frequencies of the eNOS GT+TT genotypes and T allele in the CHD group were significantly higher than that in control group (P0.05) ;and the frequency of the eNOS GT and TT genotypes between the different number of affected vessels was not significantly different in CHD( P0.05).Conclusions: eNOS894 site G→T mutation is associated with the presence of CHD in Dongxiang ethnic minority population,but has not relationship with the severity of CHD." @default.
- W2352207029 created "2016-06-24" @default.
- W2352207029 creator A5090050349 @default.
- W2352207029 date "2010-01-01" @default.
- W2352207029 modified "2023-09-22" @default.
- W2352207029 title "Correlation of Endothelial Nitric Oxide Synthase Gene G894T Polymorphism with Coronary Heart Disease on Dongxiang Ethnic Minority" @default.
- W2352207029 hasPublicationYear "2010" @default.
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