Matches in SemOpenAlex for { <https://semopenalex.org/work/W2352209972> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W2352209972 abstract "Objective:Recording bio-electrical activity from isolated rat hippocampal slices at heroin withdrawal period after chronic heroin administration and normal rat hippocampal slices in vitro at heroin acute perfusion,to observe the characteristic changes.Methods:The isolated hippocampal slices from rat model at acute withdrawal following chronic heroin administration,or normal rat hippocampal slices using two different concentrations of heroin by direct reperfusion were prepared,respectively,and the electrical activity of neurons were recorded in hippocampal CA1 area.Results:At withdrawal state after chronic heroin administration:the passive electrical properties of rat hippocampal CA1 neurons showed no significant difference compared with the control,but the half-width duration and 10%-90% decaytime of action potential significantly shortened(P0.05,P0.01);the average discharge frequency increased(P0.01)by 1.6-2.0 nA intracellular stimulus;the amplitude of excitatory postsynaptic potential(EPSP)in CA1 pyramidal neurons was reinforced significantly(P0.01).At acute heroin administration:0.3 mmol·L-1 heroin by direct perfusion,the absolute values of membrane resting potential and threshold potential decreased(P0.05,P0.01),the half-with duration and 10%-90% decaytime of action potential were elongated(P0.05,P0.01);membrane slope resistance was enlarged(P0.01),and the amplitude and the curve area of EPSP decreased significantly(P0.01).Conclusion:The bio-electrical properties of hippocampus CA1 pyramidal neurons in two administration states present significant differences." @default.
- W2352209972 created "2016-06-24" @default.
- W2352209972 creator A5077786760 @default.
- W2352209972 date "2009-01-01" @default.
- W2352209972 modified "2023-09-28" @default.
- W2352209972 title "RECORDING BIO-ELECTRICAL ACTIVITY IN RAT HIPPOCAMPAL CA1 AREA UNDER A STATE OF ACUTE OR CHRONIC HEROIN ADMINISTRATION" @default.
- W2352209972 hasPublicationYear "2009" @default.
- W2352209972 type Work @default.
- W2352209972 sameAs 2352209972 @default.
- W2352209972 citedByCount "0" @default.
- W2352209972 crossrefType "journal-article" @default.
- W2352209972 hasAuthorship W2352209972A5077786760 @default.
- W2352209972 hasConcept C112592302 @default.
- W2352209972 hasConcept C126322002 @default.
- W2352209972 hasConcept C134018914 @default.
- W2352209972 hasConcept C148762608 @default.
- W2352209972 hasConcept C169760540 @default.
- W2352209972 hasConcept C17077164 @default.
- W2352209972 hasConcept C181911157 @default.
- W2352209972 hasConcept C185592680 @default.
- W2352209972 hasConcept C2778903686 @default.
- W2352209972 hasConcept C2780035454 @default.
- W2352209972 hasConcept C2781161787 @default.
- W2352209972 hasConcept C42219234 @default.
- W2352209972 hasConcept C71924100 @default.
- W2352209972 hasConcept C86803240 @default.
- W2352209972 hasConcept C98274493 @default.
- W2352209972 hasConceptScore W2352209972C112592302 @default.
- W2352209972 hasConceptScore W2352209972C126322002 @default.
- W2352209972 hasConceptScore W2352209972C134018914 @default.
- W2352209972 hasConceptScore W2352209972C148762608 @default.
- W2352209972 hasConceptScore W2352209972C169760540 @default.
- W2352209972 hasConceptScore W2352209972C17077164 @default.
- W2352209972 hasConceptScore W2352209972C181911157 @default.
- W2352209972 hasConceptScore W2352209972C185592680 @default.
- W2352209972 hasConceptScore W2352209972C2778903686 @default.
- W2352209972 hasConceptScore W2352209972C2780035454 @default.
- W2352209972 hasConceptScore W2352209972C2781161787 @default.
- W2352209972 hasConceptScore W2352209972C42219234 @default.
- W2352209972 hasConceptScore W2352209972C71924100 @default.
- W2352209972 hasConceptScore W2352209972C86803240 @default.
- W2352209972 hasConceptScore W2352209972C98274493 @default.
- W2352209972 hasLocation W23522099721 @default.
- W2352209972 hasOpenAccess W2352209972 @default.
- W2352209972 hasPrimaryLocation W23522099721 @default.
- W2352209972 hasRelatedWork W1972482555 @default.
- W2352209972 hasRelatedWork W1973686211 @default.
- W2352209972 hasRelatedWork W1978727709 @default.
- W2352209972 hasRelatedWork W2000513117 @default.
- W2352209972 hasRelatedWork W2031387105 @default.
- W2352209972 hasRelatedWork W2041595194 @default.
- W2352209972 hasRelatedWork W2051541452 @default.
- W2352209972 hasRelatedWork W2052269807 @default.
- W2352209972 hasRelatedWork W2088455987 @default.
- W2352209972 hasRelatedWork W2104201036 @default.
- W2352209972 hasRelatedWork W2252645959 @default.
- W2352209972 hasRelatedWork W2338764267 @default.
- W2352209972 hasRelatedWork W2358130234 @default.
- W2352209972 hasRelatedWork W2370646940 @default.
- W2352209972 hasRelatedWork W2417930284 @default.
- W2352209972 hasRelatedWork W2515001975 @default.
- W2352209972 hasRelatedWork W2531755566 @default.
- W2352209972 hasRelatedWork W3029873777 @default.
- W2352209972 hasRelatedWork W3029875134 @default.
- W2352209972 hasRelatedWork W3030324185 @default.
- W2352209972 isParatext "false" @default.
- W2352209972 isRetracted "false" @default.
- W2352209972 magId "2352209972" @default.
- W2352209972 workType "article" @default.