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- W2352235814 abstract "Objective To evaluate the efficacy of adefovir dipivoxil and diammonium glycyrrhizinate in treating HbeAg-positive chronic hepatitis B.Methods Changes in symptoms,ALT levels,and HBV DNA were observed at the end of 12th and 24th week in 46 patients with HbeAg-positive chronic hepatitis B who were treated with adefovir dipivoxil and diammonium glycyrrhizinate(Group A).The same was done in 39 patients with HbeAg-positive chronic hepatitis B who were treated with adefovir dipivoxil alone(Group B).Results The amelioration of symptoms of weakness,loss of appetite,and discomfort in the hepatic region and decreased levels of ALT in Group A were more significant than in Group B at the end of week 12(P0.01).The difference in the decreased levels of ALT was more significant(P0.01) than those levels in Group B at the end of week 24,but the amelioration of symptoms of weakness,loss of appetite,and discomfort in the hepatic region was not(P0.05).The level of HBV DNA in both Group A and Group B significantly decreased at the end of week 12 and week 24,but the decreased level of HBV DNA in Group A was less significant than that in Group B(P0.05).Conclusion Adefovir dipivoxil and diammonium glycyrrhizinate have higher efficacy than adefovir dipivoxil alone." @default.
- W2352235814 created "2016-06-24" @default.
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- W2352235814 date "2010-01-01" @default.
- W2352235814 modified "2023-09-24" @default.
- W2352235814 title "Clinical observation of the treatment of patients with HbeAg-positive chronic hepatitis B using adefovir dipivoxil combined with diammonium glycyrrhizinate" @default.
- W2352235814 hasPublicationYear "2010" @default.
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