Matches in SemOpenAlex for { <https://semopenalex.org/work/W2352253778> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2352253778 abstract "Objective To observe the impact of Xinfeng capsules on the expression of VEGF- A( A- vascular endothelial growth factor) mRNA in synovial tissue in the rats of adjuvant arthritis and explore the effect mechanism of Xinfeng Capsules on synovial angiogenesis in rheumatoid arthritis. Methods Fifty Wistar rats were randomized into 5 groups,named a normal control group,a model control group,a Methotrexate group,a Tripterygium Glycosides group and a Xinfeng Capsules group,10 rats in each one. Except in the normal control group,Freund's adjuvant complete was adopted to establish the adjuvant arthritis rat model in the rest groups. After success modeling,the medicine was applied for gastric infusion accordingly and continuously for 30 days. SP immunohistochemical method was used to determine synovial microvessel density( MVD). PCR assay was used to determine the expression of VEGF- A mRNA in synovial tissue of the rats in each group. Results Compared with the normal control group,the swelling degree of volapedis and arthritis index were increased,the level of MVD and expression of VEGF- A mRNA in synovial tissue were increased significantly in the rats of the model group( P 0. 01). Compared with the model control group,the level of MVD and expression of VEGF- A mRNA were reduced significantly in Methotrexate group( P 0. 01). Compared with Xinfeng Capsules group,MVD level was increased in Methotrexate group( P 0. 05). Conclusion Xinfeng Capsules reduce the expression of VEGF- A mRNA in synovial tissue so that the medicine plays the role of the inhibition on synovial angiogenesis in the rats." @default.
- W2352253778 created "2016-06-24" @default.
- W2352253778 creator A5015688529 @default.
- W2352253778 date "2013-01-01" @default.
- W2352253778 modified "2023-09-26" @default.
- W2352253778 title "Impact of Xinfeng Capsules on the Expression of VEGF- A mRNA in Synovial Tissue in the Rats of Adjuvant Arthritis" @default.
- W2352253778 hasPublicationYear "2013" @default.
- W2352253778 type Work @default.
- W2352253778 sameAs 2352253778 @default.
- W2352253778 citedByCount "0" @default.
- W2352253778 crossrefType "journal-article" @default.
- W2352253778 hasAuthorship W2352253778A5015688529 @default.
- W2352253778 hasConcept C126322002 @default.
- W2352253778 hasConcept C134018914 @default.
- W2352253778 hasConcept C142724271 @default.
- W2352253778 hasConcept C167734588 @default.
- W2352253778 hasConcept C194671627 @default.
- W2352253778 hasConcept C203014093 @default.
- W2352253778 hasConcept C204232928 @default.
- W2352253778 hasConcept C2777025900 @default.
- W2352253778 hasConcept C2777077863 @default.
- W2352253778 hasConcept C2777575956 @default.
- W2352253778 hasConcept C2777652487 @default.
- W2352253778 hasConcept C2780394083 @default.
- W2352253778 hasConcept C2781059491 @default.
- W2352253778 hasConcept C2781079059 @default.
- W2352253778 hasConcept C59822182 @default.
- W2352253778 hasConcept C71924100 @default.
- W2352253778 hasConcept C86803240 @default.
- W2352253778 hasConceptScore W2352253778C126322002 @default.
- W2352253778 hasConceptScore W2352253778C134018914 @default.
- W2352253778 hasConceptScore W2352253778C142724271 @default.
- W2352253778 hasConceptScore W2352253778C167734588 @default.
- W2352253778 hasConceptScore W2352253778C194671627 @default.
- W2352253778 hasConceptScore W2352253778C203014093 @default.
- W2352253778 hasConceptScore W2352253778C204232928 @default.
- W2352253778 hasConceptScore W2352253778C2777025900 @default.
- W2352253778 hasConceptScore W2352253778C2777077863 @default.
- W2352253778 hasConceptScore W2352253778C2777575956 @default.
- W2352253778 hasConceptScore W2352253778C2777652487 @default.
- W2352253778 hasConceptScore W2352253778C2780394083 @default.
- W2352253778 hasConceptScore W2352253778C2781059491 @default.
- W2352253778 hasConceptScore W2352253778C2781079059 @default.
- W2352253778 hasConceptScore W2352253778C59822182 @default.
- W2352253778 hasConceptScore W2352253778C71924100 @default.
- W2352253778 hasConceptScore W2352253778C86803240 @default.
- W2352253778 hasLocation W23522537781 @default.
- W2352253778 hasOpenAccess W2352253778 @default.
- W2352253778 hasPrimaryLocation W23522537781 @default.
- W2352253778 hasRelatedWork W1601314555 @default.
- W2352253778 hasRelatedWork W2022276433 @default.
- W2352253778 hasRelatedWork W2067077551 @default.
- W2352253778 hasRelatedWork W2335044961 @default.
- W2352253778 hasRelatedWork W2352142942 @default.
- W2352253778 hasRelatedWork W2354238693 @default.
- W2352253778 hasRelatedWork W2363448015 @default.
- W2352253778 hasRelatedWork W2368190367 @default.
- W2352253778 hasRelatedWork W2370043783 @default.
- W2352253778 hasRelatedWork W2374439889 @default.
- W2352253778 hasRelatedWork W2377875917 @default.
- W2352253778 hasRelatedWork W2378097660 @default.
- W2352253778 hasRelatedWork W2394285195 @default.
- W2352253778 hasRelatedWork W2410194753 @default.
- W2352253778 hasRelatedWork W2411616343 @default.
- W2352253778 hasRelatedWork W2419458286 @default.
- W2352253778 hasRelatedWork W2980937791 @default.
- W2352253778 hasRelatedWork W2991592819 @default.
- W2352253778 hasRelatedWork W3030709760 @default.
- W2352253778 hasRelatedWork W3031761110 @default.
- W2352253778 isParatext "false" @default.
- W2352253778 isRetracted "false" @default.
- W2352253778 magId "2352253778" @default.
- W2352253778 workType "article" @default.