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- W2352292772 abstract "F]Fluoro L dopa ( 18 FDOPA) is synthesized from the starting material nitro vera traldehyde via multi step reaction by nucleophilic displacement combined with chiral catalytic phase transfer alkylation techniques and the enantiomeric purity of 18 FDOPA is determined by HPLC method using a chiral mobil phase and reversed phase C18 column. The results show that the total time of synthesis is less than 120 min, the total radiochemical yield from potassium [ 18 F ]fluoride is about 6.3 % with decay correction and the enantiomeric purity and radiochemical purity are high than 95 % and 99 %, respectively. The practical techniques are provided for the radiochemical synthesis and entiomeric purity determination of 18 FDOPA and other [ 18 F]fluoro L amino acids." @default.
- W2352292772 created "2016-06-24" @default.
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- W2352292772 date "2001-01-01" @default.
- W2352292772 modified "2023-09-25" @default.
- W2352292772 title "SYNTHESIS OF 6-[~(18)F]FLUORO-L-DOPA" @default.
- W2352292772 hasPublicationYear "2001" @default.
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