Matches in SemOpenAlex for { <https://semopenalex.org/work/W2352309515> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W2352309515 abstract "Objective Validation of pig to monkey as an experimental animal model for the study of the influence of whole-body γ-radiation on the immune system of T cells.Methods In this experiment, pig and monkey were, respectively, selected as donor and recipient. Donor and recipient were divided randomly into two groups. The blank group(group A): recipients didn't accept any treatments but heart xenotransplantation;Whole body irradiation(WBI) group(group B): received 3 Gy( 60 Co) WBI on d-30 before transplantation, the other treatments were the same as group A ; The evolution of the lymphocyte and its subsets CD4,CD8 count was followed for up to 14 days after irradiation in pigs exposed to whole body γ radiation at dose 3 Gy. The mixed lymphocyte culture was applied before WBI and after one week and two weeks.Results Compared with the pre-irradiation levels, the lymphocyte and its subsets CD4,CD8 count showed a significant decrease after irradiation, especially CD8 T cell. The results of MLC stated stimulating effect after 1 week of irradiation decreased notablely compared with the pre- irradiation levels . The survival time of donor heart in group B was longer than group A.Conclusion WBI at dose 3 Gy could clean most of the lymphocytes in the peripheral blood and its injury was limited. The CD8 T cell is more sensible to the irradiation just as in human. The irradiation in recipient exposed to whole-body γ-radiation is an effectable second means to induce immunity tolerance." @default.
- W2352309515 created "2016-06-24" @default.
- W2352309515 creator A5050592454 @default.
- W2352309515 date "2002-01-01" @default.
- W2352309515 modified "2023-09-25" @default.
- W2352309515 title "The Influence of Whole-body γ-radiation on the Immune System of T Cells in the Monkey" @default.
- W2352309515 hasPublicationYear "2002" @default.
- W2352309515 type Work @default.
- W2352309515 sameAs 2352309515 @default.
- W2352309515 citedByCount "0" @default.
- W2352309515 crossrefType "journal-article" @default.
- W2352309515 hasAuthorship W2352309515A5050592454 @default.
- W2352309515 hasConcept C111337013 @default.
- W2352309515 hasConcept C121332964 @default.
- W2352309515 hasConcept C126322002 @default.
- W2352309515 hasConcept C16685009 @default.
- W2352309515 hasConcept C167672396 @default.
- W2352309515 hasConcept C185544564 @default.
- W2352309515 hasConcept C203014093 @default.
- W2352309515 hasConcept C2776694085 @default.
- W2352309515 hasConcept C2776755627 @default.
- W2352309515 hasConcept C2777761686 @default.
- W2352309515 hasConcept C2778442404 @default.
- W2352309515 hasConcept C2778880498 @default.
- W2352309515 hasConcept C2911091166 @default.
- W2352309515 hasConcept C71924100 @default.
- W2352309515 hasConcept C86803240 @default.
- W2352309515 hasConcept C8891405 @default.
- W2352309515 hasConceptScore W2352309515C111337013 @default.
- W2352309515 hasConceptScore W2352309515C121332964 @default.
- W2352309515 hasConceptScore W2352309515C126322002 @default.
- W2352309515 hasConceptScore W2352309515C16685009 @default.
- W2352309515 hasConceptScore W2352309515C167672396 @default.
- W2352309515 hasConceptScore W2352309515C185544564 @default.
- W2352309515 hasConceptScore W2352309515C203014093 @default.
- W2352309515 hasConceptScore W2352309515C2776694085 @default.
- W2352309515 hasConceptScore W2352309515C2776755627 @default.
- W2352309515 hasConceptScore W2352309515C2777761686 @default.
- W2352309515 hasConceptScore W2352309515C2778442404 @default.
- W2352309515 hasConceptScore W2352309515C2778880498 @default.
- W2352309515 hasConceptScore W2352309515C2911091166 @default.
- W2352309515 hasConceptScore W2352309515C71924100 @default.
- W2352309515 hasConceptScore W2352309515C86803240 @default.
- W2352309515 hasConceptScore W2352309515C8891405 @default.
- W2352309515 hasLocation W23523095151 @default.
- W2352309515 hasOpenAccess W2352309515 @default.
- W2352309515 hasPrimaryLocation W23523095151 @default.
- W2352309515 hasRelatedWork W1991823666 @default.
- W2352309515 hasRelatedWork W2006238377 @default.
- W2352309515 hasRelatedWork W2017714245 @default.
- W2352309515 hasRelatedWork W2044189349 @default.
- W2352309515 hasRelatedWork W2092907204 @default.
- W2352309515 hasRelatedWork W2104956774 @default.
- W2352309515 hasRelatedWork W2112002831 @default.
- W2352309515 hasRelatedWork W2353247448 @default.
- W2352309515 hasRelatedWork W2354375432 @default.
- W2352309515 hasRelatedWork W2377800389 @default.
- W2352309515 hasRelatedWork W2391531084 @default.
- W2352309515 hasRelatedWork W2414019753 @default.
- W2352309515 hasRelatedWork W2473032752 @default.
- W2352309515 hasRelatedWork W250598985 @default.
- W2352309515 hasRelatedWork W2982600934 @default.
- W2352309515 hasRelatedWork W3024183419 @default.
- W2352309515 hasRelatedWork W3028703496 @default.
- W2352309515 hasRelatedWork W3029288168 @default.
- W2352309515 hasRelatedWork W3031591794 @default.
- W2352309515 hasRelatedWork W3032799408 @default.
- W2352309515 isParatext "false" @default.
- W2352309515 isRetracted "false" @default.
- W2352309515 magId "2352309515" @default.
- W2352309515 workType "article" @default.