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- W2352425142 abstract "Objective To provide an accurate and scientific method of radionuclide imaging for the clinical application and to study the value of SPECT imaging in detection and localization of the lesions in diagnosing pyelonephritis and renal scars in children, we evaluated the sensitivitiy and specificity of planar and planar+SPECT imaging with 99 Tc m DMSA renal scan in diagnosing the pyelonephritis and renal scars in an experimental piglet model of pyelonephritis and renal scars established in this hospital Methods We surgically created vesicoureteral reflux (VUR) in 13 female Chinese piglets, then we introduced Escherichia coli broth culture into the bladder of those presenting VUR two weeks later 99 Tc m DMSA renal scan (planar and SPECT) was performed before and after introducing infection by VETEX dual headed SPECT, then the animal and compared the images with histopathological findings were sacrificed At last, there were 7 piglets left, including 9 kidneys with abnormal renal scan and 4 kidneys with normal renal scan were analized Results The sensitivity of planar imaging was 71 2%, specificity was 100%, accuracy was 87 5% Using planar+SPECT imaging, the sensitivity of diagnosing pyelonephritis and renal scars was 78 3%, specificity was 100%, accuracy was 90 5% Conclusions 99 Tc m DMSA renal scan is a sensitive method in detection of pyelonephritis and renal scars Using planar+SPECT imaging may improve the sensitivity in detecting the foci and much more accurately evaluate the extent of the foci than using planar imaging only" @default.
- W2352425142 created "2016-06-24" @default.
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- W2352425142 date "2000-01-01" @default.
- W2352425142 modified "2023-10-03" @default.
- W2352425142 title "Detection of pyelonephritis and renal scars by ~(99)Tc~m-DMSA renal scan: an experimental study in piglets" @default.
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