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- W2352474826 abstract "Objective:To study the adapted changes of carbohydrate in the lungs of chronic hypoxic mice. Methods:The mice were divided into 2 groups (control group and hypoxia group) randomly. The lung sections were stained and assayed by the periodic acid Schiff (PAS) method after hypoxia (10%) for 1,3,5 and 7 days,and then observed by microscope. Results:The glycogen synthesis in hypoxia pulmonary arterial smooth muscle cells was higher than that in the tracheal smooth muscle cells,but it only lasted for 1-2 days;The sensitivity of glycometabolism in pulmonary veinal endothelial cell was higher than that in the pulmonary arterial endothelial cells,and it maintained the high glycometabolism during hypoxia;Hypoxia stimulated mucin secretion in the airway epithelial mucous goblet cells. The secretion and distribution of the mucin changed along with the duration of hypoxia. Conclusion:The glycometabolism and mucin secretion in the lungs of chronic hypoxic mice are adapted gradually. The secretion of high molecular weight mucus glycoproteins by submucosal glands and goblet cells formed a barrier of the airway,it is help for adapting to the chronic hypoxia." @default.
- W2352474826 created "2016-06-24" @default.
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- W2352474826 date "2002-01-01" @default.
- W2352474826 modified "2023-09-25" @default.
- W2352474826 title "Changes carbohydrate in lungs of chronic hypoxic mice" @default.
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