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- W2352477859 abstract "Interferon-stimulated gene 15(ISG15)is a kind of ubiquitin(Ub)-like protein,which is coded by isg15 gene under interferon stimulation.It is similar to Ub in sequence,structure and function,which can covalently modify target protein by enzyme cascade.ISG15 and its Ub-like modification system participate in the immune response,which is an important pathway for the interferon exerting antiviral effect.It is demonstrated thatISG15 could play antiviral activity against various viruses,including retrovirus,large DNA virus,positive-strand virus and negative-strand virus,et al.In this paper,we synthesized the research achievements in recent years,introduced ISG15 and its Ub-like modification system briefly,and discussed ISG15 antivirus activity as well as its mechanism in detail." @default.
- W2352477859 created "2016-06-24" @default.
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- W2352477859 date "2014-01-01" @default.
- W2352477859 modified "2023-09-23" @default.
- W2352477859 title "Progress on Ubiquitin-like Protein ISG15" @default.
- W2352477859 hasPublicationYear "2014" @default.
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