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- W2352477987 abstract "Objective:To investigate the significance of matrix metalloproteinase-2(MMP-2)expression in rat abdominal aortic aneurysms(AAA)models.Methods:Wistar rats underwent a120min perfusion via the abdominal aorta with50U/ml porcine pancreatic elastase or N.S.Aortic diameter was measured before and after performance of elastase perfusion and before they were sacraficed at Days0,2,7or14.At death,the aortic tissues were either fixed for histologic evaluation or extracted for immunohistochemistry and in situ histohybridization evaluation.Results:Immunohistochemistry and in situ hybridization study revealed that MMP-2increased(2～14d)consistently and paralleled to the degree of fibrotic reaction after elastase perfusion.Conclusions:MMP-2plays an evident role in the formation of abdominal aortic aneurysms and correlates to the degree of fibrotic reaction." @default.
- W2352477987 created "2016-06-24" @default.
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- W2352477987 date "2003-01-01" @default.
- W2352477987 modified "2023-09-26" @default.
- W2352477987 title "The Expression and Significance of Matrix Metalloproteinase-2 in Rat Abdominal Aortic Aneurysm Models" @default.
- W2352477987 hasPublicationYear "2003" @default.
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