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- W2352497231 abstract "AIM: To evaluate the efficacy and safety of fluoxetine, made in Shanghai, on depressive disorder. METHODS: The 16 depressive patients were randomly allocated to fluoxetine and amitriptyline treated groups with a double-blind methods. Eight patients (M 4, F 4, age 51±s 15 a) were treated with fluoxetine 20 mg po, qd, for 6 wk. Eight patients (M 3, F 5, age 51±16 a) were treated with amitriptyline 75 mg, po, bid for 6 wk. RESULTS: Each group reached significant diminishment on total scores of HAMD, HAMA and SDS, but they showed no significant difference between two groups. Each group had a effective rate 75%. The TESS scores of fluoxetine group were lower than those of amitriptyline group after 1, 2, 6 wk. CONCLUSION: Fluoxetine has a good antidepressive efficacy that is the same as that of amitriptyline. The side effects of fluoxetine are milder than those of amitriptyline." @default.
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- W2352497231 date "1997-01-01" @default.
- W2352497231 modified "2023-09-28" @default.
- W2352497231 title "Fluoxetine vsamitriptyline in treatment of 16 depressive disorders with a double-blind study" @default.
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